Faecal Microbiota Transplant (FMT) Trials


As promised, I’ve got something a little left-field for the London-based of you: details of a range of new clinical trials, led by some of my colleagues at King’s College London and St Thomas’ Hospital.

It’s all about faecal microbiota transplants (FMTs) – the transplant of faecal matter donated by a healthy person into the large intestine of someone who is ill, to restore the balance of the microbiota in the latter’s gut. If you’re intrigued by the potential of this cutting edge treatment, we’d love it if you would consider taking part either as:

1️⃣ DONOR: if you’re in good health, you could give a poop sample to use in either the trials or treating those with resistant C.diff gut infections.

2️⃣ RECIPIENT: if you have liver disease or arthritis, and are seeking a potential solution, you could be eligible to take part in this novel treatment.


There are currently three clininical trials that you may want to take apart in:

  • FERARO. A prospective, randomised placebo controlled feasibility trial of Faecal microbiota Transplant to ERadicate gastrointestinal carriage of Antibiotic Resistant Organisms.
  • PROMISE. A PROspective double-blind placebo-controlled multicentre trial of faecal MIcrobiota tranSplantation to improve outcomEs in patients with liver cirrhosis.
  • Versus Arthritis. A double-blind placebo-controlled feasibility trial to assess the tolerability and safety of FMT therapy for reducing inflammation and symptoms in Axial Spondyloarthritis (axSpA).

If interested in taking part, please get in touch with Dr Blair Merrick ([email protected])

For all the details of the three clinical trials follow the link.